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Conclusions Compared with TZD, GLP-1RA had better effects on liver fat content, body mass index, and waist circumference in overweight or obese patients with NAFLD or NASH

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Side Effects and Contraindications respiratory depression sedation constipation nausea vomiting euphoria confusion respiratory depression/arrest visual disturbances dyskinesia hallucinations delirium narcotic ileus muscle rigidity addiction loss of consciousness hypotension coma death The use of fentanyl is contraindicated in patients in the following situations (58) : After biliary tract operative interventions, hepatic elimination of the drug may be slowed